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John A Hey Selected Research

Antitussive Agents (Antitussives)

1/2009Effect of a novel NOP receptor agonist (SCH 225288) on guinea pig irritant-evoked, feline mechanically induced and canine infectious tracheobronchitis cough.
7/2004Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.
1/2002Antitussive effect of nociceptin/orphanin FQ in experimental cough models.

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John A Hey Research Topics

Disease

12Cough
03/2010 - 01/2002
5Alzheimer Disease (Alzheimer's Disease)
12/2020 - 06/2017
5Asthma (Bronchial Asthma)
04/2005 - 03/2002
3Hyperventilation
01/2008 - 07/2002
3Pneumonia (Pneumonitis)
08/2007 - 07/2002
3Allergic Rhinitis
07/2003 - 10/2002
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2018 - 06/2017
2Vomiting
01/2018 - 07/2002
2Constipation
07/2004 - 01/2002
2Nasal Obstruction
07/2003 - 11/2002
2Bronchial Spasm
08/2002 - 07/2002
2Chronic Obstructive Pulmonary Disease (COPD)
08/2002 - 07/2002
1Disease Progression
12/2020
1Edema (Dropsy)
12/2020
1Amyloid Plaque
12/2020
1Cognitive Dysfunction
01/2020
1Atrophy
01/2020
1Cerebral Cortical Thinning
01/2020
1Memory Disorders (Memory Loss)
01/2018
1Nausea
01/2018
1Ventricular Tachycardia
09/2009
1Ventricular Fibrillation
09/2009
1Sudden Death
09/2009
1Torsades de Pointes (Torsade de Pointes)
09/2009
1Hyperplasia
08/2007
1Pulmonary Edema
07/2006
1Neurogenic Inflammation
04/2005
1Pain (Aches)
04/2005
1Urinary Incontinence
04/2005
1Urticaria (Hives)
03/2005
1Skin Diseases (Skin Disease)
03/2005
1Respiratory Insufficiency (Respiratory Failure)
07/2004
1Bone Diseases (Bone Disease)
08/2003
1Bone Resorption
08/2003
1Chronic Bronchitis
01/2003

Drug/Important Bio-Agent (IBA)

6Capsaicin (Zostrix)FDA Link
03/2010 - 08/2002
4tramiprosateIBA
01/2020 - 06/2017
4Codeine (Codeine Phosphate)FDA LinkGeneric
03/2010 - 01/2002
3Amyloid beta-PeptidesIBA
12/2020 - 06/2017
3ALZ-801IBA
12/2020 - 01/2018
3NociceptinIBA
03/2010 - 01/2002
3Peptides (Polypeptides)IBA
03/2010 - 07/2004
3Antitussive Agents (Antitussives)FDA Link
01/2009 - 01/2002
3Opioid Analgesics (Opioids)IBA
01/2009 - 01/2002
3TachykininsIBA
01/2008 - 08/2002
3AntigensIBA
12/2006 - 05/2004
2Biomarkers (Surrogate Marker)IBA
12/2020 - 01/2020
2Amyloid (Amyloid Fibrils)IBA
12/2020 - 01/2018
2Pharmaceutical PreparationsIBA
01/2018 - 06/2017
2LigandsIBA
01/2009 - 07/2004
2MucinsIBA
08/2007 - 03/2006
2AerosolsIBA
12/2006 - 11/2002
2Histamine (Histamine Dihydrochloride)FDA Link
05/2004 - 10/2002
2p-Methoxy-N-methylphenethylamineIBA
07/2003 - 10/2002
2Nasal Decongestants (Decongestants)IBA
07/2003 - 11/2002
2AllergensIBA
05/2003 - 07/2002
1Apolipoprotein E4IBA
12/2020
1gantenerumabIBA
12/2020
1lecanemabIBA
12/2020
1aducanumabIBA
12/2020
1Apolipoproteins E (ApoE)IBA
01/2020
1ApolipoproteinsIBA
01/2020
1ProdrugsIBA
01/2018
1Proteins (Proteins, Gene)FDA Link
06/2017
1BaclofenFDA LinkGeneric
03/2010
1Hydrocodone (Dihydrocodeinone)FDA LinkGeneric
03/2010
18- (bis(2- chlorophenyl)methyl)- 3- (2- pyrimidinyl)- 8- azabicyclo(3.2.1)octan- 3- olIBA
03/2010
1Dextromethorphan (Racemethorphan)FDA LinkGeneric
03/2010
1Nociceptin ReceptorIBA
09/2009
1Histamine H1 AntagonistsIBA
09/2009
1Terfenadine (Seldane)IBA
09/2009
1AstemizoleIBA
09/2009
1Butorphanol (BC 2627)FDA LinkGeneric
01/2009
13-(2-(aminomethyl)phenyl)-8-(bis(2 chlorophenyl)methyl)-8-azabicyclo (3.2.1)octan-3-olIBA
01/2009
1GTP-Binding Proteins (G-Protein)IBA
01/2009
1Irritants (Vesicants)IBA
01/2009
1Interleukin-8B ReceptorsIBA
08/2007
1LipopolysaccharidesIBA
08/2007
12- hydroxy- N,N- dimethyl- 3- (2- ((1- (5- methylfuran- 2- yl)propyl)amino)- 3,4- dioxocyclobut- 1- enylamino)benzamideIBA
08/2007
1OvalbuminIBA
12/2006
1Periodic AcidIBA
07/2006
1ImmunosorbentsIBA
03/2006
1EnzymesIBA
03/2006
1AntibodiesIBA
03/2006
1TRPV1 receptorIBA
04/2005
1NeuropeptidesIBA
04/2005
1Histamine Antagonists (Antihistamines)IBA
03/2005
1Ro 64-6198IBA
07/2004
1Propofol (Diprivan)FDA LinkGeneric
05/2004
13- (2- methoxybenzylamino)- 2- phenylpiperidineIBA
02/2004
1Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA
02/2004
1Phenylpropanolamine (Dexatrim)FDA Link
07/2003
1Anti-Allergic Agents (Antiallergic Agents)IBA
05/2003
1Tachykinin Receptors (Tachykinin Receptor)IBA
01/2003
1RimonabantIBA
11/2002
1Vasoconstrictor AgentsIBA
11/2002
1TRPV Cation ChannelsIBA
11/2002

Therapy/Procedure

3Therapeutics
06/2017 - 08/2003
2Oral Administration
03/2010 - 01/2009
1Aftercare (After-Treatment)
05/2004